I should have just a couple more secondary quest before I can start the remaining main quest. I need to find Ector to give him the voice box. I also decided to attack most guards rather than sneak past them. Hilariously fun.. :-)
Alright! It was tough as I had a hunter alien on my heels the whole time, but I was able to reach Nicole, who was attached to the Marker. I defeated her (eventually) and made my escape with Ellie. What a cool game. Final boss and game ending! Great stream!