Cut the Hospital level into two parts. Assimilated all A.I. matrices but lacking the RPG in order to get into some secrets areas.
Alright! It was tough as I had a hunter alien on my heels the whole time, but I was able to reach Nicole, who was attached to the Marker. I defeated her (eventually) and made my escape with Ellie. What a cool game. Final boss and game ending! Great stream!